In vitro activity of ciprofloxacin against aerobic gram-negative bacteria.

نویسندگان

  • J E Rudin
  • C W Norden
  • E M Shinners
چکیده

For 177 gram-negative isolates, the MICs for ciprofloxacin ranged from 0.02 microgram/ml (Escherichia coli) to 0.31 microgram/ml (Pseudomonas aeruginosa). In time-kill curves, ciprofloxacin at 8 X the MIC almost completely killed 10(6) CFU of P. aeruginosa by 24 h. Ciprofloxacin at 4 X the MIC allowed bacterial regrowth by 24 h, with development of partial resistance to ciprofloxacin.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 26 4  شماره 

صفحات  -

تاریخ انتشار 1984